This is an observational cross-sectional study that was carried out on 60 rheumatoid arthritis patients who fulfilled the ACR/EULAR2010 classification criteria of RA attending to Rheumatology and Rehabilitation inpatient and outpatient clinics at Zagazig University Hospitals. To assess whether RDW and MPV can be used to follow disease activity in RA patients. To evaluate the relation between RDW and MPV with disease activity of rheumatoid arthritis. Two of these hemogram parameters are red cell distribution width (RDW) and mean platelet volume (MPV). Unos valores altos de VPM, un conteo de plaquetas que muestra las funciones de plaquetas y un conteo alto de eosinófilos son factores importantes que pueden desempeñar un papel en la etiopatogenia de la DE vasculogénica del pene.Hemogram parameters have been recently proposed as markers of inflammation in various studies from different parts of the world. No se observó ninguna diferencia significativa estadísticamente entre los 2 grupos cuando se consideraron los valores de edad, glóbulos blancos, glóbulos rojos y hemoglobina (p = 0,332, p = 0,235, p = 0,127 y p = 0,696, respectivamente). Resultados bajos de IIFE en el grupo de DE vasculogénica comparados con el grupo de control y resultados altos de CE, VPM y PC fueron detectados como estadísticamente significativos (p < 0,001, p = 0,026, p = 0,009 y p = 0,029, respectivamente). Las comparaciones intergrupales fueron realizadas utilizando el test U de Mann-Whitney y el test de la chi cuadrado (χ 2) para analizar la relación entre los variable categóricos en los grupos de pacientes. En el estudio participaron 49 pacientes en el grupo de DE vasculogénica del pene y 30 pacientes en el grupo de control. Según el resultado de la UDP, los pacientes con deficiencia vascular fueron incluidos en el grupo de DE vasculogénica del pene y los pacientes con resultados normales fueron incluidos en el grupo de control. Se utilizó la ultrasonografía Doppler peneana (UDP) en pacientes en los que se sospechaba DE vasculogénica. Se examinaron los valores de hormonas, el conteo total de sangre y otros valores de laboratorio. Dependiendo de su historial médico, el grado de DE fue determinado midiendo el índice internacional de función eréctil (IIFE). Se evaluó a los pacientes referidos con quejas de DE. Se investigó si los valores de conteo de eosinófilos (CE), el conteo de plaquetas (CP) y el volumen plaquetario medio (VPM), entre los parámetros predictivos sospechados de afectar las funciones vasculares, contribuyen a la patología de DE o no. Los parámetros de conteo de sangre de los pacientes referidos con disfunción eréctil (DE) vasculogénica del pene fueron examinados en este estudio. High MPV value and platelet count showing the platelet functions and high eosinophil count are important factors which may play a role in penile vasculogenic ED etiopathogenesis. No statistically significant difference was observed among the two groups when age, white blood cells, red blood cells or hemoglobin values are considered ( p = 0.332, p = 0.235, p = 0.127, p = 0.696, respectively). Low IIEF score in vasculogenic ED group compared to the control group and high EC, MPV and PC values were detected to be statistically significant ( p < 0.001, p = 0.026, p = 0.009, p = 0.029, respectively). Intergroup comparisons were performed using the Mann–Whitney U test and the chi-square (χ 2) test was used to assess the relationship between categorical variables within the patient groups. 49 patients participated in the study from the penile vasculogenic ED group and 30 patients from the control group. According to PDU result, patients with vascular deficiency were included in the penile vasculogenic ED group and patients with normal results were included in the control group. Penile doppler ultrasonography (PDU) was performed in patients suspected to have vasculogenic ED. Values such as hormones, complete blood count and other laboratory markers were examined. Depending on the medical story, ED degree was determined by measuring International Index of Erectile Function (IIEF). Patients referring erectile dysfunction complaint were evaluated. It was investigated whether eosinophil count (EC), platelet count (PC) and mean platelet volume (MPV), values among the suspected predictive parameters which may affect vascular functions, have a contribution on ED pathology or not. Blood count parameters of patients referring with penile vasculogenic erectile dysfunction (ED) were examined in this study.
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